Ouabain exacerbates activation-induced cell death in human peripheral blood lymphocytes
نویسندگان
چکیده
منابع مشابه
Ouabain exacerbates activation-induced cell death in human peripheral blood lymphocytes.
Lymphocytes activated by mitogenic lectins display changes in transmembrane potential, an elevation in the cytoplasmic Ca2+ concentrations, proliferation and/or activation induced cell death. Low concentrations of ouabain (an inhibitor of Na+,K+-ATPase) suppress mitogen-induced proliferation and increases cell death. To understand the mechanisms involved, a number of parameters were analyzed us...
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ژورنال
عنوان ژورنال: Anais da Academia Brasileira de Ciências
سال: 2005
ISSN: 0001-3765
DOI: 10.1590/s0001-37652005000200008